POLYOX™ WSR - N12K FP NF Grade

1 of 31 products in this brand
POLYOX™ WSR - N12K FP NF Grade composed of ethylene oxide copolymers and polyethylene oxide, serves diverse functions in pharmaceutical formulations. It finds application in abuse-deterrent tablets and capsules, gels, osmotic pump tablets, and regular tablets. This versatile ingredient acts as a binder, thickener, and controlled release agent, ensuring optimal performance. Available in powder form, it demonstrates water solubility, facilitating easy integration into formulations for enhanced effectiveness.

Functions: Binder, Controlled Release Agent, Film Former, Flocculant, Lubricant, Lubricant (Internal), Thickener, Viscosity Modifier

Manufacturing Technology: Other Manufacturing Technologies

Dosage Form: Abuse Deterrent Tablets & Capsules, Gels, Osmotic Pump Tablet, Tablets

Certifications & Compliance Search Terms: National Formulary (NF)

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Enhanced TDS

Identification & Functionality

Chemical Family
Ethylene Oxide Copolymers,
Polyethers
Chemical Name
Polyethylene Oxide
Country of Origin
United States of America (USA)
Pharma & Nutraceuticals Functions
Binder,
Controlled Release Agent,
Lubricant,
Thickener,
Viscosity Modifier
Plastics & Elastomers Functions
Binder,
Film Former,
Flocculant,
Lubricant (Internal)
Technologies
Pharmaceuticals & Nutraceuticals
Product Families
Pharmaceuticals & Nutraceuticals — Excipients
Base Fluids, Glidants & Lubricants,
Binders & Disintegrants,
Formulation & Processing Aids,
Modified & Controlled Release

Features & Benefits

Materials Features
Crosslinkable,
Drag Reduction,
Excellent Thermoplasticity,
Good Thickening Properties,
Good Wet Adhesion Strength,
High Binding Power,
Low Moisture Absorption,
Low Toxicity,
Non-Ionic,
Viscoelastic,
Water Soluble

Applications & Uses

Markets
Healthcare & Pharma
Applications
Healthcare & Pharma — Drug Delivery & Care Solutions
Oral,
Topical
Segments
Pharmaceutical
Applications
Pharmaceutical — Controlled release
Compatible Polymers & Resins
Cellulose & Cellulosics,
Ethylene Vinyl Acetate (EVA),
Polycaprolactone (PCL),
Polyethylenes (PE),
Polystyrenes (PS),
Polyurethanes (PU),
Polyvinyl Acetate (PVA),
Polyvinyl Alcohol (PVOH)
Dosage Form
Abuse Deterrent Tablets & Capsules,
Gels,
Osmotic Pump Tablet,
Tablets
Manufacturing Technology
Other Manufacturing Technologies
Plastics & Elastomers Processing Methods
Blow Molding,
Casting,
Compression Molding,
Injection Molding,
Single Screw Extrusion

Properties

Physical Form
Powder
Soluble In
Propylene Glycol Soluble,
Water Soluble
Physical Properties
ValueUnitsTest Method / Conditions
pH (at 2%, aqueous solution)8.0 - 10.0-PSM 102175
Typical Properties
ValueUnitsTest Method / Conditions
Identification (A,B)*Pass-Current Usp/Ep/Jp
Loss on Drying0.0 - 1.0%PSM 102188
Residue on Ignition0.0 - 2.0%Current NF
Viscosity (at 2% aqueous solution, Brookfield Rvf, spindle 3, speed 10 rpm, 25°C)400 - 800mPa.sBrookfield , PSM 101962
Alkaline Earth Metals (as calcium oxide)0.0 - 1.0%PSM 102225
Composition
ValueUnitsTest Method / Conditions
Silicon Dioxide Content0.8 - 3.0%PSM 101992
Butylated Hydroxytoluene Content100 - 1,000mg/kgPSM 102192
Free Ethylene Oxide Content0 - 1mg/kgPSM 102104
Heavy Metals
ValueUnitsTest Method / Conditions
Heavy Metals0.001wt.%-
Screen Test
ValueUnitsTest Method / Conditions
Screen (< 250 micron, through 60 mesh)96 - 100%PSM 102261
Note
  • The following specifications apply to sealed, unopened containers stored under the recommended conditions for the duration of the shelf life.
  • All section names come under PHS
  • * Audit Basis[AB]

Regulatory & Compliance

Certifications & Compliance Search Terms
National Formulary (NF)
Chemical Inventories
AICS (Australia),
DSL (Canada),
EINECS (EU),
ELINCS (EU),
ENCS (Japan),
IECSC (China),
ISHL (Japan),
KECI (Korea),
NDSL (Canada),
NZIoC (New Zealand),
PICCS (Phillipines),
TSCA (USA)
Quality Standards
GMP

Packaging & Availability

Packaging Type
Boxes,
Drums