METHOCEL™ A15C Premium Methylcellulose

1 of 65 products in this brand

METHOCEL™ A15C Premium Methylcellulose finds applications in suspension, tablet coating, and granulation for tablets and capsules. It is used in food containers and packaging. Features include being sewage-sludge-free. Functions as a controlled release agent, immediate release agent, thickener, solubilizer, viscosity modifier, binder, film former, gelling agent, and mucoadhesive. It is water-soluble.

Functions: Binder, Controlled Release Agent, Emulsifier, Film Former, Gelling Agent, Immediate Release Agent, Lubricant (Internal), Mucoadhesive, Plasticizer, Rheology Modifier, Solubilizer, Surfactant, Thickener, Viscosity Modifier

Manufacturing Technology: Granulation, Tablet Coating

Dosage Form: Capsules, Suspension, Tablets

Certifications & Compliance Search Terms: National Formulary (NF)

Safety Data Sheet Brochure

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Enhanced TDS

Identification & Functionality

Chemical Family: Cellulose & Cellulosics,
Cellulose Ethers
Chemical Name: Methylcellulose
INCI Name: Methylcellulose
Cosmetic Ingredients Functions: Thickener
Pharma & Nutraceuticals Functions: Binder,
Controlled Release Agent,
Film Former,
Gelling Agent,
Immediate Release Agent,
Mucoadhesive,
Solubilizer,
Thickener,
Viscosity Modifier
Plastics & Elastomers Functions: Binder,
Emulsifier,
Film Former,
Lubricant (Internal),
Plasticizer,
Rheology Modifier,
Surfactant
Technologies: Cosmetic Ingredients,
Pharmaceuticals & Nutraceuticals
Product Families: Pharmaceuticals & Nutraceuticals — Excipients
Binders & Disintegrants,
Emulsifiers & Stabilizers,
Formulation & Processing Aids,
Modified & Controlled Release,
Pharmaceutical Coatings,
Solvents & Solubilizers
Cosmetic Ingredients — Functionals
Rheology Modifiers

Features & Benefits

Food Ingredients Features: Cold Water Dispersible
Materials Features: Anti-settling Properties,
Good Gelling Behaviour,
Good Thickening Properties,
Good pH Stability,
Improved Adhesion,
Non-Ionic,
Water Soluble,
Wide pH Range

Applications & Uses

Markets: Healthcare & Pharma,
Personal Care
Applications: Personal Care — Beauty & Care
Oral Care
Healthcare & Pharma — Drug Delivery & Care Solutions
Oral
Healthcare & Pharma — Other Healthcare & Pharma Applications
Segments: Dietary Supplement,
Pharmaceutical
Applications: Pharmaceutical — Immediate release
Dietary Supplement — Immediate release
Application Format: Rinse Off
Dosage Form: Capsules,
Suspension,
Tablets
Manufacturing Technology: Granulation,
Tablet Coating
Oral Care Applications: Mouthwash,
Toothpaste

Properties

Physical Form

Soluble In

Cold Water Soluble,

Organic Solvent Soluble,

Propylene Glycol Soluble,

Physical Properties


	Value	Units	Test Method / Conditions
Opalescence	Pass	-	Current EP Opalescence
Color Evaluation	Pass	-	Current EP Solution Color
pH (at 2%)	5.0 - 8.0	-	Current USP/EP/JP

Typical Properties


	Value	Units	Test Method / Conditions
Identification*	Pass	-	Current USP/EP/JP
Residual Solvents*	Pass	-	Current USP/EP/JP
Sulfated Ash Content	max. 1.5	%	Current USP/EP/JP
Moisture Content (Loss on Drying)	max. 5.0	%	Current USP/EP/JP
Residue on Ignition	max. 1.5	%	CURRENT USP/JP
Apparent Viscosity (at 20°C, 2% in Water, Target)	1,298 - 2,422	mPa.s	Current USP/EP/JP, Brookfield

Microbiological Values


	Value	Units	Test Method / Conditions
E. coli*	Absent	/g	Current USP
Pseudomonas aeruginosa*	Absent	/g	Current USP NEGATIVE
Salmonella*	Absent	/10g	Current USP NEGATIVE
Staphylococcus aureus*	Absent	/g	Current USP NEGATIVE
Yeast and Mold Count*	max. 100	/g	Current USP Combined Mold and Yeast
Total Plate Count*	max. 100	/g	Current USP Total Aerobic

Composition


	Value	Units	Test Method / Conditions
Methoxyl Content	27.5 - 31.5	%	Current USP/EP/JP

Heavy Metals


	Value	Units	Test Method / Conditions
Cadmium Content	max. 0.1	mg/kg	E464
Mercury Content	max. 0.1	mg/kg	E464
Lead Content	max. 0.1	mg/kg	E461
Arsenic Content	max. 0.1	mg/kg	E464

Note

All section names come under PHS.
The following specifications apply to sealed, unopened containers stored under the recommended conditions for the duration of the shelf life.
Audit Basis*

Regulatory & Compliance

Certifications & Compliance Search Terms: National Formulary (NF)
Chemical Inventories: AIIC (Australia),
CSCL (Japan),
DSL (Canada),
EINECS (EU),
ENCS (Japan),
IECSC (China),
ISHL (Japan),
KECI (Korea),
METI (Japan),
PICCS (Phillipines)
Quality Standards: EN ISO 9001:2015,
GMP,
ICH Q3D

Packaging & Availability

Packaging Type: Bags,
Boxes,
Drums,
Super Sacks