Microcrystalline Cellulose is purified, partially depolymerized cellulose prepared by treating alpha cellulose obtained as a pulp from fibrous plant material with mineral acids. Several grades of Avicel® PH MCC are available varying in particle size distribution, density and moisture content. Avicel® PH microcrystalline cellulose (MCC) is most often used as a filler, disintegrant, flow aid, and dry binder for tablets and capsules. Avicel® PH-105 has a typical average particle size of 20 µm and moisture content of not more than 5%. Avicel® PH-105 is primarily used in small amounts (5-10%) with other Avicel® MCC grades, like Avicel® PH-102 and PH -101, to boost tensile strength of a tablet. Avicel® PH-105 has smallest particle size thus increasing cellulose surface area for hydrogen bonding resulting in most compactable of the Avicel® PH products.

Chemical Name: Cellulose, Microcrystalline

CAS Number: 9004-34-6

Functions: Binder, Compression Aid

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Enhanced TDS

Identification & Functionality

Applications & Uses

Properties

Physical Form
Microbiological Values
ValueUnitsTest Method / Conditions
Aerobic plate countmax. 1000cfu/gM 20-19
Mold and yeastmax. 100cfu/gM 20-20
SalmonellaAbsent/10gM 20-24
Escherichia coliAbsent/10gM 20-22
Staphylococcus aureusAbsent/10gM 20-23
Pseudomonas aerugenosaAbsent/10gM 20-21
Total coliformmax. 10cfu/gM 20-25
Nutritional Information
ValueUnitsTest Method / Conditions
Estimated Caloric Value194Cal-
Calories from Fat0Cal-
Total Fat0.0g-
Saturated Fat0.0g-
Trans-Fat0g-
Polyunsaturated Fat0.0g-
Monounsaturated Fat0.0g-
Cholesterol0.0mg-
Sodium5.0mg-
Salt0.01g-
Potassium0.0mg-
Total Carbohydrate0.0g-
Sugars (Total)0g-
Added Sugars0.0g-
Starch0g-
Total Dietary Fiber97g-
Dietary Fiber (Soluble)0g-
Dietary Fiber (Insoluble)97g-
Protein0.0g-
Vitamin A0mcg-
Vitamin C0.0mg-
Vitamin D0.0mcg-
Calcium Content1mg-
Iron Content0.0mg-
Magnesium Content0.0mg-
Moisture Content3g-
Ash Content0g-
Organic Acid0g-
Specifications
ValueUnitsTest Method / Conditions
Moisture Contentmax. 5.0%G 5-6
Water Soluble Substancesmax. 12 mg/5 gramsmg/5 gramsA 14-8
Residue on Ignitionmax. 0.05%G 5-11
Heavy Metalsmax. 0.001%G 5-7
pH5 - 7-A 11-5
Conductivitymax. 120micromhos-
Speck Countmax. 4/100gG 5-9A
Speck Countmax. 50/100gG 5-9A
Sieve Fractionmax. 0.1%Wt. %G 5-9A, Alpine
Sieve Fractionmax. 1.5%Wt. %G 5-9A, Alpine
Ether Soluble Substances**max. 5mg/10gA 14-17
Ether Soluble Substancesmax. 0.05%A 14-17
Assay**97 - 102%-
IdentificationPassess-A 11-2B
StarchNegative--
Arsenic Content**max. 3ppm-
Note

**monitor on a periodic basis per Test Method A 14-17

Regulatory & Compliance

Certifications & Compliance Search Terms

Storage & Handling

Shelf Life
4 Years