Avicel® PH - 102SCG

1 of 18 products in this brand

Microcrystalline Cellulose is purified, partially depolymerized cellulose prepared by treating alpha cellulose obtained as a pulp from fibrous plant material with mineral acids. Several grades of Avicel® PH MCC are available varying in particle size distribution, density and moisture content. Avicel® PH microcrystalline cellulose (MCC) is most often used as a filler, disintegrant, flow aid, and dry binder for tablets and capsules. Avicel® PH-102 SCG is specialized course grade primarily used for direct compression, and dry granulation/roller compaction

Chemical Name: Cellulose, Microcrystalline

CAS Number: 9004-34-6

Dosage Form: Capsules, Granules, Pellets, Tablets

Certifications & Compliance: European Pharmacopeia (Ph. Eur.), Japan Pharmacopeia (JP)

Manufacturing Technology: Direct Compression, Dry Granulation, Wet Granulation

Technical Data Sheet Safety Data Sheet Brochure

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Enhanced TDS

Identification & Functionality

Chemical Family: Cellulose & Cellulosics
Chemical Name: Cellulose, Microcrystalline
Pharma & Nutraceuticals Functions: Binder,
Compression Aid,
Filler
Technologies: Pharmaceuticals & Nutraceuticals
Product Families: Pharmaceuticals & Nutraceuticals — Excipients
Binders & Disintegrants,
Fillers & Diluents,
Formulation & Processing Aids

Applications & Uses

Markets: Healthcare & Pharma
Applications: Healthcare & Pharma — Drug Delivery & Care Solutions
Oral
Segments: Pharmaceutical
Applications: Pharmaceutical — Controlled release
Pharmaceutical — Immediate release
Dosage Form: Capsules,
Granules,
Pellets,
Tablets
Manufacturing Technology: Direct Compression,
Dry Granulation,
Wet Granulation

Properties

Soluble in

Copper Tetrammine Hydroxide

Physico-Chemical Properties


	Value	Units	Test Method / Conditions
Loss on Drying	3.0 - 5.0	%	-
Bulk Density	0.28 - 0.34	g/cc	-
Identification (A,B)	Passes	-	-
Degree of Polymerization	max. 350	units	-
pH	5.5 - 7.0	-	-
Conductivity	max. 75	μS/cm	-
Residue on Ignition	max. 0.05	%	-
Water Soluble Substances	max. 12.5	mg/5g	-
Water Soluble Substances	max. 0.25	%	-
Ether Soluble Substances	max. 0.050	%	-
Ether Soluble Substances	max. 5.0	mg/10g	-

Microbiological Values


	Value	Units	Test Method / Conditions
Total Aerobic Microbial Count	max. 100	cfu/g	-
Total Yeast and Mold Count	max. 20	cfu/g	-
Pseudomonas aeruginosa	Absent	10g	-
E. coli	Absent	10g	-
Staphylococcus aureus	Absent	10g	-
Salmonella	Absent	/10g	-
Coliform	Absent	10g	-

Specifications


	Value	Units	Test Method / Conditions
Particle Size Distribution (D10)	1 - 90	-	-
Particle Size Distribution (D50)	100 - 205	-	-
Particle Size Distribution (D90)	220 - 400	-	-
Sieve Fraction (+100 mesh (150 microns))	min. 23	wt.%	-
Sieve Fraction (+200 mesh (75 microns))	min. 57	wt.%	-

Heavy Metals


	Value	Units	Test Method / Conditions
Heavy Metals	max. 0.001	%	-

Regulatory & Compliance

Certifications & Compliance: European Pharmacopeia (Ph. Eur.),
Japan Pharmacopeia (JP)
Certifications & Compliance Search Terms: National Formulary (NF)
Chemical Inventories: AICS (Australia),
DSL (Canada),
ECL (Korea),
EINECS (EU),
ELINCS (EU),
IECSC (China),
NDSL (Canada),
PICCS (Phillipines)
Quality Standards: EN ISO 9001:2015,
ISO 22000

Packaging & Availability

Packaging Type: Boxes

Storage & Handling

Shelf Life: 4 years
Storage Conditions: Store at ambient conditions. Keep containers sealed; material is very hygroscopic.